Ciprofloxacin + Metronidazole + Terbinafine HCl + Clobetasol Propionate Cream - Manufacturers & Suppliers - Third Party Contract Manufacturing - PCD Pharma Franchise

Product Description

Comply-TM Cream is a broad-spectrum dermatological formulation that combines four powerful active ingredients Ciprofloxacin, Metronidazole, Terbinafine HCl, and Clobetasol Propionate. This unique multipurpose combination is designed to treat a wide range of bacterial, fungal, and inflammatory skin infections. It provides fast relief from symptoms such as redness, itching, swelling, irritation, burning, and scaling.

Dermatologists commonly prescribe this cream for conditions including ringworm, athlete’s foot, jock itch, rosacea, psoriasis, dermatitis, and other mixed skin infections where both microbes and inflammation are present. Comply-TM is trusted for its rapid action, strong infection control, and enhanced skin recovery.

Mechanism of Action

This cream works through the synergistic activity of four different therapeutic agents:

1. Ciprofloxacin (Antibiotic)

• Prevents bacteria from repairing, dividing, and multiplying.
• Leads to rapid destruction of a wide variety of gram-positive and gram-negative bacteria.

2. Metronidazole (Antibacterial + Antiprotozoal)

• Specifically targets anaerobic bacteria and parasites.
• Destroys microbial DNA, stopping the infection at its source.

3. Terbinafine Hydrochloride (Antifungal)

• Blocks the formation of ergosterol, an essential component of fungal cell membranes.
• Weakens the fungal structure, preventing growth and causing fungal death.

4. Clobetasol Propionate (Corticosteroid)

• Reduces inflammation by blocking prostaglandins and other inflammatory chemicals.
• Quickly relieves itching, redness, swelling, and skin irritation.

Combined Effect:
Together, these four ingredients control bacteria, fungi, parasites, and inflammation, resulting in effective management of severe or mixed skin infections.

Indications

Comply-TM Cream is recommended for:

• Ringworm (Tinea infections)
• Athlete’s foot
• Jock itch
• Psoriasis
• Rosacea
• Eczema & dermatitis
• Bacterial skin infections
• Fungal infections with inflammation
• Mixed-origin skin infections

Directions for Correct Usage

To ensure safety and maximum effectiveness, follow these usage guidelines:

• Use the cream exactly as prescribed by your dermatologist.
• Clean and dry the affected skin area before application.
• Apply a thin, even layer of the cream to the infected region.
• Wash your hands before and after applying the cream.
• Avoid using the cream in the eyes, mouth, nose, ears, or on open wounds.
• If accidental contact occurs, rinse thoroughly with clean water.
• Do not apply more than recommended, as it may increase side effects.

Side Effects

Although generally safe, improper use or excessive application can lead to mild side effects such as:

• Dryness
• Redness
• Itching
• Peeling of the skin
• Burning or stinging sensation

Precautions

• Not for ophthalmic, oral, or intravaginal use.
• Avoid long-term or large-area application unless approved by a doctor.
• Not recommended for children unless advised by a healthcare expert.
• Inform your doctor if you are pregnant, breastfeeding, or have any chronic skin conditions.
• Do not cover the treated area with tight bandages unless instructed.

Storage Instruction 

• Store the cream in a cool and dry area 
• Do not expose it it sunlight 
• Must ensure the original seal is not broken before using it first time. 

Frequently Asked Questions 

1. What is Comply-TM Cream used for?

Comply-TM Cream is used to treat various skin infections caused by bacteria, fungi, or inflammation. It is effective for ringworm, athlete’s foot, jock itch, psoriasis, rosacea, and dermatitis.

2. How does Comply-TM Cream work?

It contains four active ingredients: Ciprofloxacin to kill bacteria, Metronidazole to destroy anaerobic microbes, Terbinafine to stop fungal growth, and Clobetasol to reduce redness, itching, and swelling.

3. How long does it take for Comply-TM Cream to show results?

Most users notice improvement within 2–4 days, depending on the severity of the infection. Always complete the full recommended course.

4. Can I apply Comply-TM Cream on my face?

Use on the face only if prescribed by a dermatologist, as it contains a potent steroid (Clobetasol).

5. Is Comply-TM Cream safe for children?

It is generally not recommended for children unless advised by a pediatric dermatologist.

6. Can I use this cream for fungal infections like ringworm?

Yes, the Terbinafine in the cream is effective for fungal infections such as ringworm, athlete’s foot, and jock itch.

7. Can I cover the treated area with a bandage?

Do not cover the area with a tight bandage unless instructed by your doctor, as it may increase absorption and side effects.

8. What should I do if the cream accidentally gets into my eyes or mouth?

Rinse immediately with plenty of clean water. Seek medical help if irritation persists.

9. Are there any side effects of using Comply-TM Cream?

Possible mild side effects include dryness, redness, itching, peeling, or a burning sensation. Severe or persistent symptoms require medical attention.

10. Can I use Comply-TM Cream for longer than recommended?

No. Long-term use can cause skin thinning and other steroid-related issues. Use strictly as prescribed.